Immunological Approaches to Understanding QPX Disease
Principal Investigator:Robert S. Anderson
Start/End Year:2003 to 2006
Institution:Chesapeake Biological Laboratory, University of Maryland Center for Environmental Science
QPX is an emerging disease affecting cultured M. mercenaria from Atlantic Canada to Virginia. A suite of quantitative immunoassays will be carried out in order to understand the basis of the clams' susceptibility to this protistan parasite. Parameters of host defense such as pathogen recognition, inhibition of replication, and killing of QPX organisms by circulating blood cells and serum molecules will be measured.