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R/A-03
A Novel Approach to Inducing Sterility in Farmed Fish: Disrupting the Early Establishment of the GnRH System
Principal Investigator:
Yonathan ZoharStart/End Year:
2003 - 2006Institution:
Center of Marine Biotechnology, University of Maryland Biotechnology InstituteTopic(s):
- Striped Bass
Description:
To develop a simple and generic treatment for inducing sterility in farmed fish, that is based on altering the migration pattern of GnRH neurons during early development using gamma-aminobutyric acid (GABA). The hybrid striped bass will be the studied model. This goal includes the following objectives: I. Study the early development of the GnRH and GABA systems and of the gonads. II. Study the effect of GABA and agonists on the establishment and expression of the GnRH system. III. Study the effect of GABA and agonists, and of altered GnRH development patterns, on gonadal development, associated endocrine factors and growth rate. IV. Optimize and scale up a GABA-based treatment for the induction of sterility in hybrid striped bass and other farmed species.
Funding Start Year
2003
Funding End Year
2006
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Featured Fellow
Nina Santos is a Ph.D. student at the Chesapeake Biological Laboratory at the University of Maryland Center for Environmental Science. For her dissertation, she is focused on small shrimp-like crustaceans called mysids – an understudied yet important part of many estuarine and coastal food webs.
Featured Research Project
Developing a habitat model for mysids, an important link in Chesapeake Bay food webs
Mysids are important mesozooplankton prey for many species of fish in Chesapeake Bay and are an important link in transferring energy from lower to upper trophic levels. Mysids also serve as biological vectors for benthic-pelagic coupling due to their diel vertical migration and omnivorous prey-switching behavior, which makes mysids important regulators of food web architecture. Despite their central role in coastal food webs, surprisingly little is known about mysid ecology and dynamics in Chesapeake Bay.
Chesapeake Quarterly Magazine
The Nature of Learning: Environmental Education for the Next Generation
