R/F-71

Effects of environmental contaminants on cell-mediated immune mechanisms of the oyster

Principal Investigator:

Robert S. Anderson

Start/End Year:

1990 - 1991

Institution:

Chesapeake Biological Laboratory, University of Maryland Center for Environmental Science

Topic(s):

Description:

The production of cytotoxic oxygen metabolites by oyster blood cells will be quantified by state-of-the-art assays measuring biochemical events associated with hemocyte-mediated destruction of pathogens. Hemocytes from oysters exposed to sub-lethal concentrations of model pollutants will also be studied to identify immunotoxicological responses. Our data will define mechanisms of disease resistance, as well as unique biomarker assays for chemical stress.

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