Science Serving Maryland's Coasts

R/ODR-09

Comparative Pathogenesis of P. marinus disease in bivalves: Development of Prevention Strategies for C. virginica

Principal Investigator: 

Robert S. Anderson

Start/End Year: 

1997 to 2000

Institution: 

Chesapeake Biological Laboratory, University of Maryland Center for Environmental Science

Topic(s): 

Description: 

To identify the basis of P. marinus pathogenicity to C virginica the following host-parasite interactions will be quantified in P. marinus susceptible and -resistant bivalves: phagocytosis and antimicrobial activity, effects of cellular and serum factors on parasite replication, and the production of host immunoregulatory molecules by P. marinus The in vivo effects of b-glucan, a stimulator of antimicrobial activity, administration will be evaluated on the progression and lethality of dermo disease.