R/BT-01

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Development of immunoassays for striped bass gonadotropins

Principal Investigator:

Yonathan Zohar

Start/End Year:

1994 - 1997

Institution:

Center of Marine Biotechnology, University of Maryland Biotechnology Institute

Co-Principal Investigator:

Rosemary Jagus, Center for Marine Biotechnology, University of Maryland Biotechnology Institute

Topic(s):

Description:

To develop radioimmunoassays (RIAS) for the measurement of the striped and white bass major reproductive hormones, the gonadotropins (GtH-I&II). To enable monitoring GtH levels in striped and white bass broodfish exposed to environmental or hormonal manipulations. To use a novel recombinant DNA approach for expressing immunoactive GtHs and for developing RIAs for fish gonadotropins.

Related Publications:

Wong, TT; Zohar, Y. 2004. Novel expression of gonadotropin subunit genes in oocytes of the gilthead seabream (Sparus aurata). Endocrinology145(11):5210 -5220. doi:10.1210/en.2004-0558. UM-SG-RS-2004-13.

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