R/F-75

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Molecular recognition in host-parasite/bacterial pathogen interactions for two invertebrate models: Crassostrea virginica vs. Perkinsus marinus and Callinectes sapidus vs. Vibrio parahaemolyticus

Principal Investigator:

Gerardo R. Vasta

Start/End Year:

1992 - 1994

Institution:

Center of Marine Biotechnology, University of Maryland Biotechnology Institute

Topic(s):

Description:

To understand the molecular interactions between an invertebrate host and its parasite or bacterial pathogen (the eastern oyster Crassostrea virginica and its parasite Perkinsus marinus and the blue crab Callinectes sapidus and strains of Vibrio parahaemolyticus) and their role against disease. To develop molecular tools that will allow us to determine the presence of cryptic infections in oyster seed stock and overwintering populations and pathogenic vibrios in blue crabs. To identify molecular markers that may help to determine which individual oysters or strains may exhibit increased resistance to the parasite for selective breeding.

The Blue Crab: Callinectes Sapidus

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