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Abstracts
Workgroup: Genetics and Oyster Populations
Physiological and Genetic Correlates of Dermo Disease Resistance in the Eastern Oyster: An Interdisciplinary Approach
Principal Investigator(s):
Co-Investigator(s):
S. Kaattari, M. Faisal, Virginia Institute of Marine Science
Funding Period: 1997-1998
Ten families of oysters containing high within- and among-family genetic variability were assessed for protease inhibitory (PI) activity against proteases of Perkinsus marinus, the pathogen causing Dermo disease. Interrelationships among family survival under field challenge, disease intensity and PI activity were examined. Families with the highest field survival had the lowest body burden of parasite cells, and the highest average PI activity. These results demonstrate the association of increased PI activity with increased disease resistance and higher field survival, and demonstrate that selectable genetic variation for these traits exists in hatchery stocks of eastern oysters.
IMPACTS and/or BENEFITS: These results confirm the feasibility of a selective breeding program for enhancing Dermo resistance, and underscore the importance of broodstock selection in such a program. In addition, they demonstrate the utility of PI activity as a measurable correlate of disease resistance, which can be used in future studies to map the responsible gene(s), and use them or closely linked markers in programs of marker-assisted selection or introgression.
PROJECT PUBLICATIONS:
Faisal, M., S. Kaattari, and P. M. Gaffney. 1998. Physiological and genetic correlates of Dermo disease resistance in the eastern oyster. Journal of Shellfish Research 17:1301.
Oliver, J. L., P. M. Gaffney, J. S K Allen, M. Faisal, and S. L. Kaattari. 2000. Protease inhibitory activity in selectively bred families of eastern oysters. Journal of Aquatic Animal Health 12:136-145.
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